#28145 Anti-Human Girdin (Phospho-Y1764) Rabbit IgG A.P.

References (0)
FAQ (0)
Related Materials (0)
Related Products (0)

References (0)
FAQ (0)
Related Materials (0)
Related Products (0)

Intended Use：: Research reagents

Application：: WB, ICC

Package Size1：: 50 μg

Package Size2：: 5 μg

Note on Application Abbreviations: WB:Western Blotting; ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	28145
Product Name	Anti-Human Girdin (Phospho-Y1764) Rabbit IgG A.P.
Maker Name	Immuno-Biological Laboratories Co., Ltd.
Intended Use	Research reagents
Application	WB, ICC
Species	Human
Immunizing antigen	Synthetic peptide of the phosphorylated part of Human Girdin (RKTEDT(pY)FISSAG)
Purification Method	Affinity purified with antigen peptide
Specificity	Cross-react with Human Phosphorylated Girdin
Package Form	Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	50 μg
Package Size 2	5 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Girdin is a new protein playing an important role in the infiltration and metastasis of cancer cells. A new substance of Akt, Girdin (Girders of actin filament) was discovered by a research group led by Takahashi et al., Nagoya University by screening using yeast two-hybrid method and was elucidated that Girdin has an important role for cell migration downstream of Akt.

It has been proven that Girdin is a new actin binding protein and it restructures actin fibers upon it is phosphorylated by Akt and it involves in forming of lamellipodia that is located at the leading edge of cells and playing an important roles for cell migration by functional analysis. Various antibodies inclusive phosphorylated Girdin antibodies are provided by IBL and it has been suggested that the change of condition of phosphorylated Girdin involves in structure alteration in relation to cell migration in vivo or in vitro by current studies used these antibodies.