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#28141 Anti-Human CAD (2194) Rabbit IgG Affinity Purify

Intended Use：
Research reagents
Application：
WB, IP
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28141
Product Name Anti-Human CAD (2194) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP
Species Human
Immunizing antigen Synthetic peptide in portion of C terminus of Human CAD（carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase）（EVDSDPRAAYFRQAENG）
Purification Method Purified with antigen peptide
Specificity Recognizes the C-terminus of human CAD (2194-2210 aa).
Package Form Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

mTOR is a target molecule in mammalian used in rapamycin drug and it has been recognized as a central molecule that has a role of signaling for regulating proliferation and cell growth. Since DNA replication is essential for proliferation, regulating system of cell growth and amino-acid perception centrally related with mTOR deeply involve with the system of biosynthesis of nucleic acid. CAD (carbamoyl phosphate synthetase, aspartate transcarbamoylase, dihydroorotase) was discovered and found its important roles in the pathway of pyrimidine biosynthesis as a result of survey for molecules related to biosynthesis of nucleic acid in a molecular complex with raptor and mLST8. CAD catalyzes an initial step in de novo synthesizing system of pyrimidine synthesis and it is regulated by phosphorylation of other protein kinases. mLST8 bridges between CAD and mTOR and CAD plays a role as signaling in mTOR pathway by a cross-interaction with mLST8. This antibody is considered as a useful tool for research in mTOR signal pathway, especially for research in regulating system of biosynthesis of nucleic acid.
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