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#28121 Anti- GFAT1 (663) Rabbit IgG Affinity Purify

  • WB
Intended Use：
Research reagents
Application：
WB, IP
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28121
Product Name Anti- GFAT1 (663) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP
Immunizing antigen Synthetic peptide of the C terminal part of GFAT1 (RGYDVDFPRNLAKSVTVE)
Purification Method Purified with antigen peptide
Specificity Cross reacts with mouse and rat.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

GFAT1 (Glutamine : fructose-6-phosphate amidotransferase 1) is one of nutrient-　sensitive　phosphoprotein which was identified as a protein phosphorylated in glucose-deprived cells. Three nutrient signaling pathways have been widely known; (i) the mammalian target of rapamycin (mTOR) signaling pathway, (ii) AMP-activated protein kinase (AMPK) signaling pathway, and (iii) hexosamine signaling pathway. GFAT1 was isolated, which is the first and rate-limiting enzyme for the entry of glucose into the hexosamine signaling pathway to generate UDP-GlcNAc in mammals. Recent evidences have indicated that the signals derived from nutrients like amino acid and glucose play important roles in the control of the cellular activities as well as in synthesis of proteins and generation of ATP.
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