Product Search

#28113 Anti- Dock8 Rabbit IgG Affinity Purify

  • WB
  • Photo is Mouse embryonic spinal cord to ventral root by Dr. Junji Yamauchi,<br /> Department of Pharmacology,<br /> National Research Institute for Child Health and Development
Intended Use：
Research reagents
Application：
WB, IP, ICC
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation
ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28113
Product Name Anti- Dock8 Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP, ICC
Immunizing antigen Synthetic peptide of a part of Human Dock8.
Purification Method Purified with antigen peptide
Specificity Reacts with human, mouse and rat.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Small GTPase of Rho family is one of signaling factors which control alteration of cellular morphology, cell division and differentiation, and plays an important role in regulation of generation and organogenesis at an individual level. Its functions are strictly regulated and its dysfunction causes many diseases such as immunological disease or neurodegenerative disease. Dedicator of cytokinesis (Dock) 8 is a Rho family small GTPase activating factor (or exchange factor) activating Rac1 and Cdc42 specifically of the Rho family small GTPase. It is considered that Dock8 is an important factor for proliferation and differentiation of immnocytes, neurocytes and stem cells since it is more expressed especially in immune system, nerve tissues and tissues of fetal stage. It is known as a responsible gene for hyper-IgE syndrome, and many types of genetic mutations have been reported. Additionally, relation with blood tumors has been pointed out. There are proteins, called Dock6 and Dock7, very similar to Dock8 in human but there are still many unclear points about their regulation systems.
Contact Us >