Product Search

#18681 Anti-Human TIMP-1 (T-172) Rabbit IgG Affinity Purify

Intended Use：
Research reagents
Application：
WB
Package Size1：
100 μg
Note on Application Abbreviations
WB:Western Blotting

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18681
Product Name Anti-Human TIMP-1 (T-172) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB
Species Human
Immunizing antigen The part of Synthetic peptide of TIMP-1 protein (177-188)
Purification Method Purified with antigen peptide
Specificity Confirmed by Recombinant TIMP-1
Package Form Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Tissue inhibitor of Metalloprotinase 1 (TIMP-1) is endogenous-specific inhibitor produced simultaneously with matrix metalloproteinase (MMP). TIMP-1 inhibits both active MMP to control degeneration of extracellular matrix (ECM) and conversion of intermediate form into active form. In addition, TIMP-1 forms complex with not only active MMP but also potential MMP. Especially, TIMP-1 binds to potential MMP-9 by affinity of C-terminal domain to one another. The degeneration of extracellular matrix is essential step in invation and metastasis of tumor cell. It is considered that tumor cell collects protease on the surface of cell and degenerates ECM in invading tissue.
Contact Us >