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#18573 Anti-Human N-Cadherin (224) Rabbit IgG Affinity Purify

  • human myocardium
Intended Use：
Research reagents
Application：
IHC
Package Size1：
100 μg
Package Size2：
10 ug
Note on Application Abbreviations
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18573
Product Name Anti-Human N-Cadherin (224) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application IHC
Species Human
Immunizing antigen Synthetic peptide of a part of human N-Cadherin
Purification Method Purified with antigen peptide
Specificity Cross reacts with rat and mouse
Package Form Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 ug
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Cadherins are a family of Ca2+-dependent intercellular adhesion molecules.　They play an important role in cell-cell interaction, histogenesis and cellular transformation, and association with the actin cytoskeleton regulates their function by a complex of cytoplasmic proteins called the catenins (α, β, γ). Among the cadherin protein family, N-cadherin function is indirectly regulated by endogenous kinases and phosphatases. Tyrosine phosphorylation of β-catenin complexed with N-cadherin results in dissociation of N-cadherin from actin. However, Thus, N-cadherin is an integral adhesion molecule whose function is regulated by protein-protein interactions and phosphorylation/dephosphorylation events.
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