Product Search

#18516 Anti-Human COX-2 (C631) Rabbit IgG Affinity Purify

  • Human lung adenocarcinoma
Intended Use：
Research reagents
Application：
WB, IHC
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18516
Product Name Anti-Human COX-2 (C631) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Synthetic peptide of a part of Human COX-2
Purification Method Purified with antigen peptide
Specificity Human COX-2 specific. Not cross-react with Human COX-1 and Rat COX-2.
Reacts with U937 cell line stimulated with TPA.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

COX-1 and COX-2 (Cyclooxygenase 1,2) are also called prostaglandin endoperoxide H synthase, and are important enzymes as catalysts for the reaction in prostaglandin H2 (PGH2) synthesis from the arachidonic acid. COX-1 and COX-2 have the homology of about 60% at the amino acid level. COX-1 is expressed constitutively in many organs such as kidney, stomach, vascular smooth muscle or platelets widely and it is thought to play a so-called housekeeping role. On the other hand, COX-2 cannot be usually detected from organs, however, it is high-level expressed by macrophage and other cells in response to the stimulation such as various cytokines, hormones, the tumor cause medicines, inflammation mediators, or mitogens, therefore, it is thought that COX-2 produces prostaglandin in relation to the inflammation condition.
Contact Us >