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#18203 Anti-Human Big-Endothelin-1 (22-38) Rabbit IgG Affinity Purify

Intended Use：
Research reagents
Application：
IHC
Package Size1：
50 μg
Package Size2：
5 μg
Note on Application Abbreviations
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18203
Product Name Anti-Human Big-Endothelin-1 (22-38) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application IHC
Species Human
Immunizing antigen Synthetic peptides of human big endothein-1 (22-38)
Purification Method Purified with antigen peptide
Specificity Endothelin-1 0%
Endothelin-2 0%
Endothelin-3 0%
Big Endothelin-1 100%
Big Endothelin-2 <0.1%
Big Endothelin-3 <0.1%
VIC <0.1%
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05% NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 50 μg
Package Size 2 5 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Endothelins are 21 amino acid peptides that are produced ubiquitously by vascular endothelial cells, smooth muscle cells, and other cells in different organs. Endothelins are secreted as big-endothelins that are converted to active proteins by the endothelin-converting enzyme. These peptides possess many biological activities, such as vasoconstriction and mitogenesis, and are involved in numerous physiological and pathophysiological processes in humans. Elevated plasma levels of endothelin have been associated with heart failure, and increased immunoreactivity for endothelin is observed in transplant coronary artery disease. Endothelin-1 (ET-1) is known as the most potent vasoconstrictor substance.
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