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- #11098 Anti-Human CRMP-2 (N3E) Mouse IgG MoAb
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#11098 Anti-Human CRMP-2 (N3E) Mouse IgG MoAb
- Intended Use:
- Research reagents
- Application:
- WB
- Package Size1:
- 100 μg
- Package Size2:
- 10 μg
- Note on Application Abbreviations
- WB:Western Blotting
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 11098 |
---|---|
Product Name | Anti-Human CRMP-2 (N3E) Mouse IgG MoAb |
Intended Use | Research reagents |
Application | WB |
Species | Human |
Immunizing antigen | Recombinant Human CRMP-2 |
Source | Mouse-Mouse hybridoma (Supernatant) (PAI x BALB/c mouse lymph nodes) |
Clone Name | N3E |
Subclass | IgG2b |
Purification Method | Affinity purified with Protein A |
Specificity | Cross-reacts with Mouse and Rat |
Package Form | Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 100 μg |
Package Size 2 | 10 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis elegans homolog of CRMP-2, results in abnormal axon termination. CRMP-2 is most ubiquitously expressed in the nervous system of CRMP-2 family, and expressed in most nerve cell at the early stage of differentiation, and further, in cone cell of hippocampus, in Purkinje cell of cerebellum and sensory neuron of dorsal root ganglion (DRG) at maturation stage. This protein is localized in axon, growth cone and cell body.
References
References
- Increased Phosphorylation of Collapsin Response Mediator protein-2 at Thr514 Correlates With β-amyloid Burden and Synaptic Deficits in Lewy Body Dementias. Xing H et al. Mol Brain. 2016 Sep 8;9(1):84.PMID: 27609071
- Proteomic analysis of time-dependent changes in proteins expressed in mouse hippocampus during synaptic plasticity induced by GABAA receptor blockade. Matsuura K et al.Neurosci Lett. 2013 Oct 25;555:18-23.PMID: 23932890
Note: Retrieve by PMID number in displayed by abstract: http://www.ncbi.nlm.nih.gov
FAQ
FAQ
-
Q.Can this antibody be used for staining?
-
A.No it cannot.