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#11071 Anti- S100 Protein (2A10) Mouse IgG MoAb

Intended Use：
Research reagents
Application：
WB, IHC
Package Size1：
1 mL
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 11071
Product Name Anti- S100 Protein (2A10) Mouse IgG MoAb
Intended Use Research reagents
Application WB, IHC
Immunizing antigen Bovine brain S-100 Protein
Source Mouse-Mouse hybridoma　(X63-Ag8.653×BALB/c spleen cells)
Clone Name 2A10
Subclass IgG1
Purification Method Purified with Protein A
Specificity React to b chain of bovine and human S-100 protein
Package Form Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 1 mL
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

S100 proteins (16 members) show a very divergent pattern of cell- and tissue-specific expression, of subcellular localizations and relocations, of post-translational modifications, and of affinities for Ca2+, Zn2+, and Cu2+, consistent with their pleiotropic intra- and extracellular functions. Up to 40 target proteins are reported to interact with S100 proteins and for S100A1 alone 15 target proteins are presently known. Therefore it is not surprising that many functional roles have been proposed and that several human disorders such as cancer, neurodegenerative diseases, cardiomyopathies, inflammations, diabetes, and allergies are associated with an altered expression of S100 proteins.
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