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#11021 Anti-Human CEA (1B2) Mouse IgG MoAb

Intended Use：
Research reagents
Application：
IHC
Package Size1：
1 mL
Note on Application Abbreviations
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 11021
Product Name Anti-Human CEA (1B2) Mouse IgG MoAb
Intended Use Research reagents
Application IHC
Species Human
Immunizing antigen Human CEA
Source Mouse-Mouse hybridoma (Supernatant)　(X63-Ag8.653×BALB/c spleen cells)
Clone Name 1B2
Subclass IgG2a
Purification Method Purified with Protein A
Specificity Not cross-react with NCA
Package Form Lyophilized product in PBS
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Not Applicable
Cartagena Not Applicable
Package Size 1 1 mL
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Carcinoembryonic antigen (CEA) was reported as cancer-specific antigen existing in human colon cancer tissue and embryo intestinal tract in 1965. However it was denied that the antigen is carcinoembryonic later. CEA exists in the blood of patients with some benign disease as well as with cancer disease. The production of CEA is observed in many cancer tissues and the CEA value in the blood reflects tumor size. Therefore, the assay is widely used in a diagnosis and in monitoring of cancer. CEA is glycoprotein which has molecular weight of about 180kDa, and is detected as broad band in globlin area in electrophoresis. The bands are due to diversity of the carbohydrate portion and the carbohydrate content in CEA is 50 - 60% The CEA includes CEA related antigens which do not cross-react with CEA antisera such as NCA (non-specific cross reacting antigen) derived from lung and spleen, NCA-2 derived from the embryo stool, NFA-1 (normal fecal antigen-1) derived from the normal adult stool and NFA-2. Code No. 10094 and 11021 are CEA-specific and do not cross-react with NCA. Code No. 11022 cross-reacts to NCA Code No. 16131 and 16133 are absorbed by NCA.
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