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#10371 Anti-Human NP95 (mt40) Mouse IgG MoAb

  • WB
Intended Use：
Research reagents
Application：
WB
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10371
Product Name Anti-Human NP95 (mt40) Mouse IgG MoAb
Intended Use Research reagents
Application WB
Species Human
Immunizing antigen Purified human NP95 protein
Source Mouse-Mouse hybridoma　(SP210 × BALB/c mouse spleen cells, ascites)
Clone Name mt40
Subclass IgG1
Purification Method Affinity purified with Protein A
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Np95 has been originally found as a tumor-specific nuclear antigen of 95kDa in mice. Experiments using B10 strains showed that Np95 is enriched in precancerous cells and is abnormally expressed throughout cell cycle in radiation-induced lymphomatoid cells. Recent attention is put on the epigenetic role of Np95, which mediates the interplay between DNA methylase and hemi-methylated sites to maintain DNA methylation patterns at replication forks. This antibody is available for detection of the human nucleoprotein NP95 (also known as UHRF1), whose function is dependent on S-phase in non-neoplastic cells but could be modified with abberant cell cycle during tumorigenesis.
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