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- #10363 Anti-Mouse BEC12 (LA5) Rat IgG MoAb
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#10363 Anti-Mouse BEC12 (LA5) Rat IgG MoAb
- Intended Use:
- Research reagents
- Application:
- IHC
- Package Size1:
- 100 μg
- Package Size2:
- 10 μg
- Note on Application Abbreviations
- IHC:Immunohistochemistry
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 10363 |
---|---|
Product Name | Anti-Mouse BEC12 (LA5) Rat IgG MoAb |
Intended Use | Research reagents |
Application | IHC |
Species | Mouse |
Immunizing antigen | Mouse lymphangioma |
Source | Rat-Mouse hybridoma |
Clone Name | LA5 |
Subclass | IgG2a, κ |
Purification Method | Affinity purified with antigen |
Specificity | Reacts to about 12 kDa protein antigen on the blood vascular endothelialmembrane of mouse. Not cross-react with endothelial cells of lymph vessels or large-medium-sizedarteries and veins, but cross-reacts with some lymphatic cells. Not cross-react with human, rat or guinea pig. |
Package Form | Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 100 μg |
Package Size 2 | 10 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
Recent years, specific antigens of vascular endothelium have been found one after another, and they contribute to progress of vascular biology.
This antibody, being unlike any other prior antibodies, reacts especially with arterial microcirculating system including small arteries and blood capillaries, and also reacts with some small venous endothelial cells. This is an unprecedented type (site-specific) of anti vascular endothelium antibody, generated with an adjuvant-induced benignant lymphangioma (intra-abdominal tumor) by “rapid differential immunization technique” (a more efficient immunization method for antigens which are weak in antigenicity.) It doesn’t react with endothelial cells of lymph vessels but reacts with some blood cells.
Photos are kindly provided by Dr. Taichi Ezaki, Department of Anatomy & Developmental Biology, Tokyo Women's Medical University School of Medicine.