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#10281 Anti-Human MBD3 (3A3) Mouse IgG MoAb

  • WB
Intended Use：
Research reagents
Application：
WB
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10281
Product Name Anti-Human MBD3 (3A3) Mouse IgG MoAb
Intended Use Research reagents
Application WB
Species Human
Immunizing antigen Synthetic peptide of part of C terminal of human MBD3 (EELARDGEAPLDKAC)
Source Mouse-Mouse hybridoma (Supernatant)　(X63-Ag8.653×BALB/c spleen cells)
Clone Name 3A3
Subclass IgG1
Purification Method Affinity purified with antigen peptides
Specificity Not cross-react with MBD2
Package Form Lyophilized product from 1% BSA in PBS containing 0.05%NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG binding domain (MBD) can bind to single methylated CpGs and most of them are involved in transcription control. So far, five vertebrate MBD proteins have been described as MBD family members: BD1, MBD2, MBD3, MBD4 and MECP2.
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