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#10221 Anti-Human Napsin A (TMU-Ad02) Mouse IgG MoAb

  • WB
  • Human lung cancer(well-differentiated adenocarcinoma)
Intended Use：
Research reagents
Application：
WB, IHC
Package Size1：
50 μg
Package Size2：
5 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10221
Product Name Anti-Human Napsin A (TMU-Ad02) Mouse IgG MoAb
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Synthetic peptide of the N-terminal part of human Napsin A
Source Mouse-Mouse hybridoma　(X63 - Ag 8.653 × BALB/c mouse spleen cells)
Clone Name TMU-Ad02
Subclass IgG1
Purification Method Affinity purified with antigen peptide
Specificity Immunohistochemical study in histopathological types of lung carcinoma
Package Form Lyophilized product from in PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 50 μg
Package Size 2 5 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

A new protein isolated by two-dimensional immuno-electrophoresis from tissue of lung adenocarcinoma was identified as Napsin A, a new aspartic Proteinase. The reactivity of the antibody showed immunohistochemically in type II pneumocytes, alveolar macrophages, renal tubules and exocrine glands and ducts in pancreas. In particular, type II pneumocytes and alveolar macrophages showed strong staining. The specificity of the antibody is very interesting, which in primary lung adenocarcinoma, 47 out of 58 (81.0%) primary lesions were positive. All well-differentiated adenocarcinoma except those of goblet type showed strong staining. The antibody may be a useful tool as a tumor marker for primary lung adenocarcinoma.
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