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#10094 Anti-Human CEA (1B2) Mouse IgG MoAb

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Intended Use：: Research reagents

Application：: IHC

Package Size1：: 200 μg

Package Size2：: 20 μg

Note on Application Abbreviations: IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	10094
Product Name	Anti-Human CEA (1B2) Mouse IgG MoAb
Intended Use	Research reagents
Application	IHC
Species	Human
Immunizing antigen	Human CEA
Source	Mouse-Mouse hybridoma　(X63 - Ag 8.653 × BALB/c mouse spleen cells)
Clone Name	1B2
Subclass	IgG2a
Purification Method	Affinity purified with protein A
Specificity	Not cross-react with NCA
Package Form	Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	200 μg
Package Size 2	20 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Carcinoembryonic antigen (CEA) was reported as cancer-specific antigen existing in human colon cancer tissue and embryo intestinal tract in 1965. However it was denied that the antigen is carcinoembryonic later. CEA exists in the blood of patients with some benign disease as well as with cancer disease. The production of CEA is observed in many cancer tissues and the CEA value in the blood reflects tumor size. Therefore, the assay is widely used in a diagnosis and in monitoring of cancer. CEA is glycoprotein which has molecular weight of about 180kDa, and is detected as broad band in β-globlin area in electrophoresis. The bands are due to diversity of the carbohydrate portion and the carbohydrate content in CEA is 50 - 60% The CEA includes CEA related antigens which do not cross-react with CEA antisera such as NCA (non-specific cross reacting antigen) derived from lung and spleen, NCA-2 derived from the embryo stool, NFA-1 (normal fecal antigen-1) derived from the normal adult stool and NFA-2. Code No. 10094 and 11021 are CEA-specific and do not cross-react with NCA. Code No. 11022 cross-reacts to NCA Code No. 16131 and 16133 are absorbed by NCA.