IBL News

Any IBL product introduced in this IBL news is applicable for research use only and it cannot be used for diagnosis or medical purpose.

We are pleased to announce that we newly released 27901 Human secreted α-Klotho Assay Kit – IBL

The α-Klotho gene was identified as a gene with extremely reduced expression in genetically mutated mice with a phenotype that closely resembles the diverse aging symptoms of humans. The long N-terminal extracellular domain, which occupies most of the sequence of the α-Klotho protein, has been reported to be shedding and released in the blood, while secretory isoform with only first repeat by gene splicing (secreted α-Klotho) has been reported. 

Since there are many unclear points regarding the function of secreted α-Klotho protein and its body fluids concentration, it has been required to establish a detection system for it. This kit specifically measures human secreted isoforms (secreted α-Klotho) and does not react with soluble α-Klotho derived from transmembrane α-Klotho.

This kit can quantify secreted α-Klotho in human serum, EDTA-plasma and cerebrospinal fluid.

【Related Products】
#27998 Human soluble α-Klotho Assay Kit - IBL
#27601 Mouse soluble α-Klotho Assay Kit - IBL

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Sales Department
Antibody related Business Division
Immuno-Biological Laboratories Co., Ltd.
Email: do-ibl@ibl-japan.co.jp

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